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Updated: May 21, 2025

Assessment of Sarcoplasmic Reticulum Calcium Reserve and Intracellular Diastolic Calcium Removal in Isolated Ventricular Cardiomyocytes
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Wnt/β-catenin通路通过AKAP6-介导的RyR2酸化和肉质细胞网膜泄漏诱导心脏功能障碍

Ang Li1, Yuanyuan Shen1, Zhenyan Li1

  • 1School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.

Journal of molecular cell biology
|March 17, 2025
PubMed
概括

在心肌细胞中,Wnt/β-catenin通路通过提高肌肉选择性A激酶定蛋白 (mAKAP) 的调节来丰富细胞质. 这导致通过泄漏导致心脏功能障碍,为心脏病提供了新的治疗点.

关键词:
在 AKAP6 里,你会看到 AKAP6.在 RyR2R2 里.正规的 Wnt 路径.心脏的稳定心脏的稳定.

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