相关实验视频
Updated: Jun 16, 2025

12:03
Fertility Preservation in Patients with Severe Ovarian Dysfunction
Published on: March 25, 2021
4.5K
索耶综合征患者的不孕症管理:一个病例报告
Laura Krygere1, Ruta Bartasiene2,3, Agne Kozlovskaja-Gumbriene3
1Department of Obstetrics and Gynaecology, Medical Academy, Lithuanian University of Health Sciences, Eiveniu Str., Kaunas, Lithuania. laura.kygere@lsmu.lt.
Journal of assisted reproduction and genetics
|March 18, 2025
概括
辅助生殖技术,如使用捐赠卵子进行体外受精 (IVF),使斯怀尔综合征的妇女能够怀孕和健康分娩. 这种罕见的性发育障碍涉及非功能性腺体,但成功的育儿是可能的.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 遗传学 遗传学 是一个
- 发展生物学 发展生物学
背景情况:
- 索耶综合征是一种罕见的性发育障碍,其特征是完全发生性腺失调.
- 关键特征包括原发性 amenorrhoea,延迟青春期,高淋巴激素和雌激素缺乏.
- 患有索耶综合征的个体有非功能性生殖腺,这给自然受孕带来了挑战.
研究的目的:
- 用辅助生殖技术报告一个患有索耶综合征的女性成功怀孕和分娩的情况.
- 为了证明在完全发生性腺失调的个体中生育治疗的有效性.
- 为了突出一个可行的生殖选择的女性与非功能性生殖腺.
主要方法:
- 一个妇女的病例报告,在18岁时被诊断出患有Swyer综合征.
- 患者接受了双边淋巴切除术和激素替代疗法.
- 在31岁时,她通过使用捐赠的卵细胞进行体外受精 (IVF) 进行生育治疗.
主要成果:
- 使用捐赠卵细胞进行的试管婴儿治疗导致了成功的,无并发症的怀孕.
- 患者通过剖腹产分娩出了一个健康的婴儿.
- 这代表了Swyer综合征患者的积极生殖结果.
结论:
- 辅助生殖技术,特别是用卵细胞捐赠进行试管婴儿,是苏耶综合征妇女成为父母的可行途径.
- 这个案例有助于了解完全发生性腺失调的女性的生殖成功.
- 特定的生殖方法可以在具有挑战性的生育病例中带来成功的结果.
相关概念视频
Infertility in Females
288
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
288
Infertility in Males
256
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
256
In Vitro Fertilization
234
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
234
Spermatogenesis
102.3K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.3K
Meiosis II
183.2K
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
183.2K
Birth Control Methods
215
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
215

