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Updated: May 21, 2025

Time-resolved Förster Resonance Energy Transfer Assays for Measurement of Endogenous Phosphorylated STAT Proteins in Human Cells
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雅克抑制剂和B细胞功能:对它们对血细胞分化,细胞因子产生和原始B细胞激活的影响进行比较研究

Wenqi Huang1, Charlotte de Vries1, Ravi Kumar Sharma1,2

  • 1Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.

European journal of immunology
|March 18, 2025
PubMed
概括

简氏激酶抑制剂 (JAKi) 影响B细胞分化,减少血细胞的形成. 不同的JAKi对B细胞激活和细胞因子产生有不同的影响,突出了它们在自身免疫性疾病中的治疗潜力.

关键词:
乙淋巴细胞 B-淋巴细胞这是一种JAK抑制剂.巴里西提尼布 (baricitinib) 是一种药物.菲尔戈提尼布 (filgotinib) 是一种药物.托法西提尼布 (tofacitinib) 是一种在此之前,upadacitinib 已经在使用中.

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