社会脆弱性指数与肺切除后的主要发病率有关
Savan K Shah1, Arsalan A Khan1, Sanjib Basu2
1Department of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Illinois.
Annals of thoracic surgery short reports
|March 18, 2025
概括
高度的社会脆弱性与早期非小细胞肺癌 (NSCLC) 患者的重大发病率和死亡率增加有关,这些患者接受了视频辅助胸腔镜肺切除. 这突显了脆弱人群手术结果的差异.
科学领域:
- 胸部外科手术 胸部外科手术
- 健康中的社会经济因素
- 在瘤学瘤学.
背景情况:
- 在接受视频辅助胸腔镜肺切除的早期非小细胞肺癌 (NSCLC) 患者中,社会脆弱性指数 (SVI) 的预后影响尚不清楚.
- 评估SVI的作用对于识别和解决手术结果的潜在差异至关重要.
研究的目的:
- 调查社会脆弱性指数 (SVI) 与早期非小细胞肺癌 (NSCLC) 患者的重大术后发病率之间的关联.
- 为了确定SVI是否是视频辅助胸腔镜肺切除后不良结果的独立预测因素.
主要方法:
- 在2010年至2021年期间接受了肺切除的IA-IIB期NSCLC551名患者的回顾性评估.
- 使用疾病控制和预防中心 (CDC) 基于地理编码地址的计算器计算SVI.
- 主要发病率是根据胸部外科医生协会的标准定义的;用于评估SVI与结果的关联的后勤回归分析.
主要成果:
- 社会脆弱性指数 (SVI) 截止值为0.831,确定了高SVI患者,这些患者不成比例地是黑人 (58%对9%).
- 高SVI患者的重大发病率显著上升 (27%对9%) 和增加1年死亡率的趋势 (8.9%对3.0%).
- 高SVI状态独立预测了30天主要发病率 (OR 3.16,P = 0.031) 即使调整了多种临床和人口因素.
结论:
- 高的社会脆弱性指数 (SVI) 与视频辅助胸腔镜肺切除非小细胞肺癌 (NSCLC) 后的主要发病率显著增加有关.
- 在这个患者群体中,SVI是术后不良结果风险的重要指标,强调了针对性干预的必要性.
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