对于妊娠年龄来说小的风险因素,定义为出生体重z-score低于零分之一:一个前性观察性研究
Hein Odendaal1, Lucy T Brink1, Anusha Lachman2
1Department of Obstetrics and Gynecology, Stellenbosch University, Cape Town, South Africa.
概括
母亲吸烟,高血压,先前的死胎和低教育水平是对怀孕年龄小的新生儿的关键风险因素. 这些发现突出了改善出生结果的干预关键领域.
科学领域:
- 产科和妇科 产科和妇科
- 围产期流行病学 围产期流行病学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 怀孕年龄较小的新生儿 (SGA) 患新生儿不良后果的风险增加.
- 确定孕产妇的风险因素对于有针对性的干预和改善妊娠护理至关重要.
研究的目的:
- 为了确定与怀孕年龄较小的新生儿相关的孕产妇风险因素,定义为出生体重z分数 (BWZS) 低于-1.0.
主要方法:
- 从2007年8月到2015年1月进行的前性队列研究.
- 分析了来自南非开普敦低社会经济水平地区同质人口的数据.
- 进一步分析安全通道研究数据.
主要成果:
- 母亲吸烟,先前死产,高血压,低教育和较低的体重指数 (BMI) 与增加SGA风险有显著的关联.
- 几率比率 (ORs) 显示,与以前的死产 (1.89) 和吸烟 (1.84) 有着强烈的关联.
- 高血压 (1.40) 和低教育 (0.94) 和BMI (0.95) 也显示出显著的关联.
结论:
- 以前的死产,吸烟,高血压,较低的教育程度和较低的BMI是孕期新生儿小的重要孕产妇风险因素.
- 这些因素是产前护理和公共卫生倡议的关键目标.
- 早期识别和管理这些风险因素可能会改善胎儿生长和出生结果.
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