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螺旋上皮质瘤与甲状腺样元素:一个案例报告

Maheen Maruf1, Sajid Mushtaq1, Umer Sheikh1

  • 1Pathology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

Cureus
|March 18, 2025
PubMed
概括

带有甲状腺样元素的螺旋上皮瘤 (SETTLE) 是一种罕见的儿科部癌症. 这一案例突出了其具有挑战性的诊断和积极性,强调了早期检测和治疗策略的必要性,以获得更好的生存结果.

科学领域:

  • 儿科瘤学 儿科瘤学
  • 手术病理学手术病理学
  • 头部和部新生体.

背景情况:

  • 带有甲状腺样元素的螺纹上皮瘤 (SETTLE) 是儿童和青少年的一种罕见的恶性瘤,通常呈现在部胀.
  • 它起源于异胎性胸腺或分支囊衍生物,并具有双相形态 (螺旋和上皮细胞) 的特征.
  • 塞特尔有晚期血液转移的倾向,由于其稀有性,经常被误诊.

研究的目的:

  • 报告儿童中出现甲状腺胀的SETTLE病例.
  • 讨论诊断方面的挑战,包括与突肉瘤和其他甲状腺瘤的区分.
  • 强调早期诊断,手术管理和SETTLE监测的重要性.

主要方法:

  • 一个儿科患者甲状腺胀的病例报告.
  • 诊断工作包括精细针吸收细胞学,全甲状腺切除术与组织病理学检查,免疫组织化学和分子分析.
  • 考虑的差异性诊断是骨髓癌,有甲状腺样元素的癌症 (CASTLE) 和突肉瘤.

主要成果:

  • 患者呈现出逐渐增加的左甲状腺胀.
  • 细胞检查发现贝塞斯达5类脊柱细胞损伤.
  • 组织病理学和免疫组织化学证实了SETTLE,排除了其他差异. 分子测试排除了突肉瘤.
关键词:
皮质上皮质上皮质上皮质.很少见 很少见 很少见 很少见脊柱上皮瘤具有类似胸腺的元素 (定居)突性肉瘤 (Synovial Sarcoma) 是一个突性肉瘤.甲状腺是什么?甲状腺是什么?

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  • 患者经历了局部复发和肺转移,在诊断后42个月屈服于疾病.

    • 结论:

    • SETTLE是一种罕见的儿科甲状腺瘤,具有明显的晚期转移风险.
    • 准确的诊断需要形态学,免疫组织化学和分子研究的结合.
    • 迅速的手术切除和警的监测对于改善SETTLE患者无病生存率至关重要.
    • 进一步报告病例对于制定复发和转移的有效治疗方案至关重要.