在选择性社交蜜蜂中,营养操纵的转录组相关性
Jesse L Huisken1, Sandra M Rehan1
1Department of Biology, York University, Toronto, ON, Canada, M3J 1P3.
The Journal of experimental biology
|March 18, 2025
概括
在木匠蜜蜂中,营养操纵不会改变基因表达,但身体大小会改变. 这表明,激素调节会影响矮人大女儿的下属行为,影响合作.
科学领域:
- 昆虫的行为昆虫的行为
- 合作合作的演变.
- 神经遗传学 神经遗传学
背景情况:
- 昆虫的亚社会行为涉及父母的照顾,可以推动合作进化.
- 对后代的营养操纵可以影响基因调节和后代大小,可能会强迫合作.
- 东部小木匠蜜蜂 (Ceratina calcarata) 呈现矮身长女 (DED),它们缺乏供应,并充当采集者.
研究的目的:
- 调查DEDs的营养操纵是否会改变大脑基因表达.
- 了解Ceratina calcarata中的合作性兄弟姐妹关怀的遗传基础.
- 确定体型,基因表达和附属行为出现之间的关系.
主要方法:
- 整个蜜蜂头的转录基因分析.
- 在自然供应的DEDs,正常女儿,实验性供应不足的女儿和补充的DEDs之间比较基因表达.
- 基因表达的分析作为连续体型的函数.
主要成果:
- 两组之间观察到基因表达的最小差异.
- 基因表达随着持续的身体大小而变化巨大,而不是离散的种姓或化顺序.
- 基因本体学 (GO) 术语丰富表明小蜜蜂的荷尔蒙调节.
结论:
- 基因表达的差异主要与绝对体型有关,而不是营养状况或种姓.
- 转录因子的荷尔蒙调节可能是DED中观察到的行为差异的基础.
- DEDs中的下属行为可能是社会环境和经验对身体尺寸和基因表达产生影响的结果.
更多相关视频
08:42Methods for Comparing Nutrients in Beebread Made by Africanized and European Honey Bees and the Effects on Hemolymph Protein Titers
Published on: March 17, 2015
10.6K
08:53Preparation of Single-cohort Colonies and Hormone Treatment of Worker Honeybees to Analyze Physiology Associated with Role and/or Endocrine System
Published on: September 6, 2016
15.8K
相关概念视频
Cis-regulatory Sequences
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
Cooperative Binding of Transcription Regulators
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome. Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form dimers that...
Master Transcription Regulators
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
Cooperative Binding of Transcription Regulators
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome. Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form dimers that...
Master Transcription Regulators
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
Transcriptional Regulation: Riboswitches
Riboswitches are RNA elements that regulate gene expression by altering their secondary structures in response to specific effector molecules. These elements, located in the leader regions of certain mRNAs, act as transcriptional regulators by toggling between alternative conformations to control downstream gene expression. Riboswitch-mediated regulation is a precise mechanism for modulating biosynthetic pathways, as exemplified by the riboflavin biosynthesis pathway in Bacillus...
