[患有骨关节炎的老年患者心脏代谢风险的特征.]
O A Osipova1, G O Savelyeva1, L V Vasilyeva2
1Belgorod National Research University, 85 Pobedy St., Belgorod 308015, Russian Federation, е-mail: osipova@bsu.edu.ru.
Advances in gerontology = Uspekhi gerontologii
|March 18, 2025
概括
患有严重膝关节关节炎 (KOA) 的老年患者患肥胖,高血压和糖尿病的比率更高. 患有严重KOA的男性患有更多的肥胖和高的LDL胆固醇,而女性患有更高的瘦素水平.
科学领域:
- 老年学是一门学科.
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 类风湿病学 类风湿病学
背景情况:
- 骨关节炎 (OA) 是老年人患的一种常见的退行性关节疾病.
- 心血管和代谢障碍是老龄化人口的重大健康问题.
- 骨关节炎严重程度和心脏代谢风险因素之间的相互作用需要进一步调查.
研究的目的:
- 确定膝关节骨关节炎 (KOA) 的老年患者可修改心脏代谢风险因素的频率.
- 根据KOA的严重程度 (Kellgren-Lawrence等级2和3) 来分析这些频率.
- 为了检查性变态对心脏代谢风险因素的影响,在这个人群中.
主要方法:
- 一项涉及154名被诊断患有膝关节关节炎的老年患者的横截面研究.
- 评估心脏代谢风险因素,包括肥胖,动脉高血压 (AH),糖尿病 (DM),吸烟,脂质特征 (LDL胆固醇,甘油三) 和耐葡萄糖.
- 评估心血管风险使用SCORE-OP尺度和测量瘦素水平.
主要成果:
- 与3级KOA患者相比,患有3级KOA患者的肥胖 (25.2%),AH (15.1%),DM (27.1%),吸烟 (94%),LDL胆固醇升高 (32.7%),高甘油三 (26.8%),葡萄糖耐受性降低 (18.4%),以及SCORE-OP风险得分较高,与2级KOA患者相比.
- 与女性相比,患有3级KOA的老年男性的肥胖率增加 (42.7%) 和LDL胆固醇升高 (37.8%).
- 患有3级KOA的女性的瘦素水平高出23.9%. 与女性相比,患有3级KOA的男性患高血压 (21.4%),糖尿病 (36.7%) 和非常高的SCORE-OP风险 (75.5%) 的比例也更高.
结论:
- 膝关节关节炎的严重程度与老年人心脏代谢风险因素的负担增加有关.
- 性二态度起着作用,在老年男性和患有严重膝关节关节炎的女性之间观察到不同的风险因素模式.
- 这些发现强调了对膝关节骨关节炎的老年患者综合管理策略的重要性,解决关节健康和心血管/代谢健康问题.
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