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Updated: Jul 15, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

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Published on: October 26, 2015

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在MEP途径中的IspC酶的非胺酸抑制剂:结构洞察力和药物开发潜力

Yaqing Zhou1, Jili Wang1, Yong Sun1

  • 1Shiyan Key Laboratory of Biological Resources and eco-Environmental Protection, College of Chemical and Environmental Engineering, Hanjiang Normal University, Shiyan, China.

Chemical biology & drug design
|March 18, 2025
PubMed
概括

针对1-Deoxy-D-xylulose-5-phosphate降低异构酶 (IspC) 的非酸盐抑制剂对于开发新药至关重要. 研究探讨了它们的结构和活性,旨在克服当前基于酸盐的抑制剂的局限性.

关键词:
斯米多米辛是一种菌.这是一种IspC抑制剂.欧洲议员的路径结合金属的药解体.没有酸盐的非酸盐

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