痴呆症患者中发作的流行率和相关因素:一项基于临床的回顾性研究
Liz Edenberg Quiles1,2, Prima Kristina Paola Quintay1, Adrian Espiritu3,4
1Department of Neurology, Institute of Neurosciences, The Medical City, Pasig City, Philippines.
Epilepsia open
|March 18, 2025
概括
在菲律宾,4.1%的痴呆症患者出现了新发作,主要是那些患有严重阿尔茨海默病的人. 这凸显了对痴呆症和发作的老年患者需要更好的管理策略的需要.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 流行病学 流行病学
背景情况:
- 菲律宾老龄化人口正在经历与年龄相关的慢性疾病如痴呆和发作的增加.
- 了解痴呆症和新发作的同时发生对于管理老年患者至关重要.
研究的目的:
- 确定在门诊环境中出现新发作发作的痴呆症患者的频率和临床特征.
- 确定与痴呆症患者发育相关的人口和临床因素.
主要方法:
- 一项描述性,回顾性研究分析了245名在马尼拉三级医院 (2010-2020年) 使用DSM-5标准诊断的痴呆症患者.
- 数据包括人口统计,痴呆症严重程度,并发症和性特征.
- 统计分析涉及描述性统计,双变量和多变量后勤回归.
主要成果:
- 10名患者 (4.1%) 发生了新发作.
- 在患有严重痴呆症的患者中,发作更频繁 (与轻度痴呆症相比,几率比率为10).
- 阿尔茨海默病是最常见的痴呆类型;一般性发作发生在50%的病例中. 发作在65-79岁年龄组中最常见.
结论:
- 在这组门诊患者中,4.1%的菲律宾痴呆症患者出现了新发作.
- 严重的痴呆症,特别是阿尔茨海默病,是发作发作的重要危险因素.
- 识别痴呆症患者的发作预测因素和特征对于改善患者管理和生活质量至关重要.
相关概念视频
Seizures: Classification
315
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
315
Dementia
108
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
108
Arteries of the Lower Limbs
181
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
181
Alzheimer's Disease: Overview
456
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
456


