一个多元组件的战略,以改善艾滋病毒暴露前预防在美国南部的监狱:协议为3型混合实施-有效性试验的协议
Ank E Nijhawan1, Jana Kholy2, Julia L Marcus3
1Department of Internal Medicine, Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
JMIR research protocols
|March 18, 2025
概括
这项研究实施了以监狱为基础的暴露前预防 (PrEP) 策略,以增加南方美国监狱中与司法有关的个人获得艾滋病预防的机会. 目标是通过将个人与释放后的护理联系起来来减少艾滋病毒健康差异.
科学领域:
- 公共卫生 公共卫生
- 实施科学 实施科学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 暴露前预防 (PrEP) 在关键人群中未得到充分利用,包括美国南部和涉及刑事法律系统的人群.
- 改善这些群体的PrEP接入可以减少艾滋病毒健康差异,并影响公共卫生,因为监狱社区的流动性很高.
- 对于涉及刑事法律的个人来说,预防艾滋病毒对公共卫生有重大影响.
研究的目的:
- 在达拉斯县监狱 (DCJ) 开发,实施和评估一个多组件的PrEP策略.
- 在涉及刑事法律的个人中增加暴露前预防 (PrEP) 的启动率.
- 为了减少高风险人群中的艾滋病毒发病率.
主要方法:
- 使用EPIS框架进行的3型混合实施效率研究.
- 定性访谈以确定PrEP连接的障碍和促进者.
- 基于EHR的HIV风险预测模型的开发和PrEP患者导航器的整合.
主要成果:
- 来自26次采访的定性调查结果为PrEP实施战略提供了信息.
- 使用EHR数据开发和验证了一种使用EHR数据的HIV风险预测模型.
- 预计2026年将有初步调查结果.
结论:
- 这项研究将为基于监狱的PrEP策略的可行性和有效性提供见解.
- 这种可扩展的策略可以作为其他城市监狱解决艾滋病毒不平等问题的典范.
- 这些发现将支持增加司法参与人口中PrEP采用率的努力.
相关概念视频
Retrovirus Life Cycles
45.5K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.5K
Healthcare Agencies II
675
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
675
Healthcare Associated Infections II: Preventive Measures
2.3K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.3K


