ABCB 运输器:其功能不仅仅扩展到辅酶运输
Ritu Devi1,2,3, Palak Arora1,2, Bhawna Verma1,2,3
1Plant Biotechnology Division, CSIR-Indian Institute of Integrative Medicine, Jammu, 180001, India.
Planta
|March 18, 2025
概括
植物ATP结合盒 (ABC) 载体,特别是ABCB亚家族,对于适应至关重要. 这些多功能蛋白调节各种过程,帮助植物在压力下生存.
科学领域:
- 植物生物学 植物生物学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 在所有生命形式中,ATP结合盒 (ABC) 蛋白质对于通过细胞膜运输各种化合物至关重要.
- 植物表现出大量的ABC载体,其中ABCG和ABCB亚家族是最普遍的.
- 众所周知,ABCB输送体是辅酶的输送体,但它们在植物生理学中具有更广泛的作用.
研究的目的:
- 审查ABCB载体在植物中的多方面的作用.
- 突出ABCB蛋白在植物适应和生存中的重要性.
- 探索药用植物中ABCB功能和二次代谢物合成之间的联系.
主要方法:
- 关于ABCB传送器的已发表研究的文献综述.
- 汇编关于ABCB本地化和功能多样性的数据.
- 分析ABCB在各种生物过程和应激反应中的作用.
主要成果:
- ABCB 运输体参与了许多植物功能,包括生长,发育,应激反应和代谢物运输.
- 它们在细胞膜中的广泛局部化促进了各种运输活动.
- 在植物适应生物和非生物环境挑战方面,ABCBs发挥着关键作用.
结论:
- ABCB亚家族成员是植物适应所必需的多功能蛋白质.
- 它们的作用超出了辅酶运输范围,包括关键的生存机制.
- 了解ABCB功能为植物弹性和药物化合物生产提供了洞察力.
更多相关视频
12:18A Strategy to Validate the Role of Callose-mediated Plasmodesmal Gating in the Tropic Response
Published on: April 17, 2016
10.2K
08:31Agrobacterium tumefaciens and Agrobacterium rhizogenes-Mediated Transformation of Potato and the Promoter Activity of a Suberin Gene by GUS Staining
Published on: March 29, 2019
29.3K
相关概念视频
01:31ABC Transporters: Exporter
4.1K
ATP-binding cassette or ABC transporter is the largest superfamily of integral membrane proteins. The transporters have transmembrane-binding domains (TMDs) and nucleotide-binding domains (NBDs). The TMDs are specific to their substrates, whereas the NBDs are similar to engines that complete ATP hydrolysis to complete the substrate transport. They can be full transporters consisting of two TMDs and NBDs, half transporters with one TMD and NBD, while some encoded with a single TMD or NBD are...
4.1K
01:27ABC Transporters: Importer
2.7K
ATP-binding cassette or ABC transporters are a class of ATP-driven pumps that hydrolyze ATP to move solutes across the membrane. They can be grouped into importers and exporters. While exporters are present in all domains of life, importers exist only in bacteria and some plants.
In bacteria, based on the number of transmembrane helices and the chemical nature of their substrates, the ABC importers can be divided into three types:
In bacteria, based on the number of transmembrane helices and the chemical nature of their substrates, the ABC importers can be divided into three types:
2.7K
01:06Carrier-Mediated Transport
225
Carrier-mediated transport is a pivotal process in drug absorption, particularly for lipid-insoluble drugs, and encompasses facilitated diffusion and active transport. Facilitated diffusion allows drugs to move along their concentration gradient without energy expenditure, while active transport utilizes ATP to drive drug movement against this gradient.
Active transport involves two types of membrane-spanning transporters: uptake and efflux. Uptake transporters are expressed in the small...
Active transport involves two types of membrane-spanning transporters: uptake and efflux. Uptake transporters are expressed in the small...
225
01:14Active Transport
396
Active transport is a critical biological process that allows cells to move solutes against an electrochemical gradient. This process requires direct energy input and is characterized by its selectivity, saturability, and susceptibility to competitive inhibition.
Primary active transporters, like Na+, K+ and -ATPase, directly utilize ATP to move ions across the membrane. These transporters play significant roles in various physiological processes. For instance, Na+, K+ and -ATPase maintain...
Primary active transporters, like Na+, K+ and -ATPase, directly utilize ATP to move ions across the membrane. These transporters play significant roles in various physiological processes. For instance, Na+, K+ and -ATPase maintain...
396
01:19Drug Absorption Mechanism: Carrier-Mediated Membrane Transport
3.4K
Certain large, lipid-insoluble drug molecules that resemble amino acids, peptides, or glucose, require specialized carrier proteins to facilitate their diffusion across cell membranes. This transport can occur through either facilitated diffusion, which does not require energy input, or active transport, which does require energy input.
Facilitated diffusion is a passive process that utilizes human Solute Carrier (SLC) transporters. These transporters bind to the drug, undergo structural...
Facilitated diffusion is a passive process that utilizes human Solute Carrier (SLC) transporters. These transporters bind to the drug, undergo structural...
3.4K
02:12Short-distance Transport of Resources
15.6K
Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
15.6K