Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

C4 Pathway and CAM01:27

C4 Pathway and CAM

45.1K
Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
45.1K
Chi-square Analysis02:46

Chi-square Analysis

36.3K
The chi-square test is a statistical hypothesis test. It is used to check whether there is a significant difference between an expected value and an observed value. In the context of genetics, it enables us to either accept or reject a hypothesis, based on how much the observed values deviate from the expected values.
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
36.3K
Catenins01:23

Catenins

2.2K
Catenins are characterized by multiple binding domains and dynamic structures that allow them to function as linker proteins in cell junction complexes. All catenins, except α-catenin, contain a characteristic protein sequence called the armadillo repeat and are therefore also called armadillo proteins.
Catenins in Cell Junctions
Catenins bind to cell adhesion molecules such as cadherins and link them to different cytoskeletal proteins depending on the type of cell junction. At the...
2.2K
Methods of Documentation V: CBE01:23

Methods of Documentation V: CBE

863
Charting by Exception, or CBE, is a method of documentation used in healthcare, particularly in nursing, that focuses on documenting only significant or abnormal findings rather than recording every detail. This approach aims to streamline the documentation process, improve efficiency, and ensure that healthcare providers can quickly identify deviations from normalcy in patient assessments.
In CBE, healthcare professionals establish predefined standards of practice that define what constitutes...
863
Computed Tomography01:10

Computed Tomography

4.2K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.2K
GPCRs Regulate Adenylyl Cylase Activity01:09

GPCRs Regulate Adenylyl Cylase Activity

5.1K
Some GPCRs transmit signals through adenylyl cyclase (AC), a transmembrane enzyme. AC helps synthesize second messenger cyclic adenosine monophosphate (cAMP). AC catalyzes cyclization reaction and converts ATP to cAMP by releasing a pyrophosphate. The pyrophosphate is further hydrolyzed to phosphate by the enzyme pyrophosphatase, which drives cAMP synthesis to completion. However, cAMP is rapidly degraded to 5′ AMP by the enzymes phosphodiesterase (PDE), preventing overstimulation of...
5.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Glaucoma Diagnosis and Progression Prediction Based on Deep Multimodal Fusion and Collaborative Attention Mechanism.

IEEE journal of biomedical and health informatics·2026
Same author

AISCT-SAM: Customized SAM-Med2D with 3D Context Awareness and Self-Prompt Generation for Fully Automatic Acute Ischemic Stroke Lesion Segmentation on Non-Contrast CT Scans.

IEEE journal of biomedical and health informatics·2026
Same author

STFusion: A Spatial-Temporal Dual-Pathway Network with Multi-scale Attention Fusion for Early Diagnosis of Parkinson's Disease.

Interdisciplinary sciences, computational life sciences·2026
Same author

Subtype-HM: A Novel Cancer Subtype Identification Method Based on Hypergraph Learning and Multi-omics Data.

Interdisciplinary sciences, computational life sciences·2025
Same author

Customized SAM-Med3D With Multi-View Representation Fusion and Age-Grade Stratified Loss for Glioma Survival Risk Prediction.

IEEE journal of biomedical and health informatics·2025
Same author

Multi-Modal Multi-Kernel Graph Learning for Autism Prediction and Biomarker Discovery.

IEEE transactions on computational biology and bioinformatics·2025

相关实验视频

Updated: May 21, 2025

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

2.0K

CA2CL:用于病态图像分析的集群意识对抗性对比学习.

Junjian Li, Hulin Kuang, Jin Liu

    IEEE journal of biomedical and health informatics
    |March 18, 2025
    PubMed
    概括

    我们介绍了集群意识的对抗性对比学习 (CA2CL),这是一种用于病理图像分析的新方法,可以克服当前对比学习技术的局限性. CA2CL增强了从未标记的数据中进行表示学习,改善了诊断模型的性能,特别是在注释有限的情况下.

    科学领域:

    • 医疗图像分析 医学图像分析
    • 计算病理学计算病理学
    • 机器学习 机器学习

    背景情况:

    • 病理诊断对于挽救生命至关重要,但需要广泛,昂贵的数据注释.
    • 目前的对比式学习方法难以产生具有挑战性的阳性样本,并遭受虚假阴性.

    研究的目的:

    • 开发一种新的对比学习方法 (CA2CL),以解决当前病理学自我监督学习的局限性.
    • 改进从未标记的病理图像中生成信息性表示.

    主要方法:

    • 拟议的集群意识的对抗性对比学习 (CA2CL) 包含混合数据增强和集群意识的损失.
    • 利用对抗式学习来生成具有挑战性的对比数据对,并学习强大的表示.
    • 在NCT-CRC-HE,PCam,Glas和CARG数据集上进行评估,用于各种任务,包括微调,线性评估,检测和细分.

    主要成果:

    • 与现有的自主监督学习方法和ImageNet预训练相比,CA2CL表现优越.
    • 特别是在数据可用性有限的场景中观察到显著的改善.
    • 该方法在微调,线性评估,检测和细分任务中表现出有效性.

    结论:

    更多相关视频

    In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
    10:44

    In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

    Published on: May 5, 2023

    1.4K
    Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
    09:05

    Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

    Published on: May 6, 2015

    10.7K

    相关实验视频

    Last Updated: May 21, 2025

    High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
    08:50

    High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

    Published on: May 12, 2023

    2.0K
    In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
    10:44

    In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

    Published on: May 5, 2023

    1.4K
    Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
    09:05

    Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

    Published on: May 6, 2015

    10.7K
  • CA2CL有效地克服了用于病理图像分析的对比学习的挑战.
  • 提出的方法为从未标记的数据中学习可靠的表示提供了有希望的解决方案,减少了对注释的依赖.
  • CA2CL在计算病理学中推进了自我监督学习,特别是在数据稀缺的环境中.