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顺尿道超声切除用于治疗局部性前列腺癌和良性前列腺增生症 (BPH)

Lucas Engelage¹, Rolf Muschter¹

¹ALTA Klinik, Bielefeld, Germany.

Journal of endourology

|March 18, 2025

概括

顺尿道超声波切除 (TULSA) 为局部性前列腺癌和BPH提供了安全有效的治疗方法. 这种MRI指导的手术在300名男性中显示出良好的结果,并发症最小,生活质量保持良好.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
医疗成像医学成像

背景情况:

顺尿道超声切除 (TULSA) 是一种新兴的微创治疗局部性前列腺癌 (PCa) 和良性前列腺增生 (BPH) 的方法.
图尔萨适用于低至中等风险的PCa,有症状的BPH和辐射后复发,提供精确的废除方法.
该程序需要专门的MRI兼容仪器和实时MRI温度计,以提供准确的治疗.

研究的目的:

评估通过尿道超声波切除术 (TULSA) 的安全性和有效性,对一大群患有局部性前列腺癌和/或BPH的男性进行评估.
评估瘤和功能结果,包括并发症率,勃起功能,尿和症状得分.
分析使用TULSA的全腺,焦点和联合PCa和BPH疗法的治疗结果.

主要方法:

一个回顾性单一中心研究包括300名接受TULSA治疗的男性,用于原发性局部性前列腺癌或BPH.
治疗包括全腺TULSA (163名男性),焦点TULSA (137名男性) 和PCa/BPH联合治疗 (88名男性).
使用磁共振成像 (MRI) 指导,机器人驱动的超声波应用器和肠直肠冷却,随访时间中位数为14个月.

主要成果:

大多数患者出现了1级或2级并发症 (57/300),这些并发症在4周内消失;七名患者出现了3级事件.
没有报告4级以上的不良事件或肠道并发症. 在96%的患者中,保持了无带体.
中位勃起功能得分保持稳定,国际前列腺症状得分在48个月后改善至基线以下.

结论:

顺尿道超声波切除 (TULSA) 是针对局部性前列腺癌和BPH的安全有效治疗方法,严重并发症的发生率较低.
图尔萨可以保持无片的尿和勃起功能,治疗后下尿路症状显著改善.
通过MRI指导的TULSA手术显示出有前途的瘤和功能结果,支持其在治疗前列腺疾病中的作用.

关键词:

泌尿病学中的MRI技术图尔萨 (Tulsa) 图尔萨 (Tulsa) 是一个城市.干预性泌尿病学干预性泌尿病学前列腺癌治疗前列腺癌治疗治疗局部性前列腺癌的治疗方法

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