右心室功能障碍在儿科急性呼吸困扰综合征中普遍存在,反映了肺高血压和右心室功能障碍
Nathan D Markiewitz1, Yan Wang2, Robert A Berg3
1Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA.
Critical care explorations
|March 18, 2025
概括
右心房 (RA) 功能障碍在儿科急性呼吸困扰综合征 (PARDS) 中很常见,几乎一半的患者在24小时内受到影响. 这种功能障碍与肺高血压和右心室 (RV) 问题有关.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 关键护理医学 关键护理医学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 右心房 (RA) 功能障碍与肺高血压和呼吸衰竭的不良结果有关.
- 在儿科急性呼吸窘迫综合征 (PARDS) 中,RA功能障碍的患病率和特征尚不清楚.
研究的目的:
- 在PARDS发作后24小时内确定RA功能障碍的患病率和模式.
- 在PARDS患者中调查RA功能障碍,肺高血压和右心室 (RV) 缩功能障碍之间的关联.
主要方法:
- 对患有PARDS的儿科患者 (<18岁) 和健康对照者的回顾性队列研究.
- 用心声图 (常规和斑点跟踪) 来评估RA和RV缩功能在PARDS诊断后24小时内.
- 统计分析包括非参数比较和相关性分析.
主要成果:
- 在92名PARDS患者中,近一半 (49%) 患有RA功能障碍,与55名对照组相比,储阶段应变减少 (40.2%对53.7%).
- 患有肺高血压的PARDS患者表现出明显较低的储阶段RA菌株 (31.7%与40.5%相比).
- 更糟糕的RA功能与更高的大脑类型的尿素水平和RV缩功能障碍相关.
结论:
- 在PARDS的早期阶段,RA功能障碍很普遍.
- 早期的RA功能障碍,特别是在储阶段,与肺高血压和RV缩功能障碍有关.
- 需要进一步的研究来探索RA功能轨迹及其对PARDS结果的影响.
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