设计和应用ISSA-BP神经网络模型来预测软组织放松力
Yongli Yan1, Teng Ren2, Li Ding1,3
11Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, China.
Acta of bioengineering and biomechanics
|March 18, 2025
概括
这项研究引入了一个增强的神经网络模型,用于在虚拟手术中精确的软组织生物机械建模. 这种新的方法显著改善了组织放松力的预测,提高了训练现实性.
科学领域:
- 生物医学工程 生物医学工程
- 计算机建模 计算建模
- 人工智能在医学中的应用
背景情况:
- 准确的生物机械建模对于现实的虚拟外科训练至关重要.
- 传统的粘弹性模型存在计算挑战和复杂性.
- 神经网络为增强软组织建模能力提供了一个潜在的解决方案.
研究的目的:
- 为软组织开发一个计算效率高,准确的生物机械模型.
- 在虚拟手术系统中增强软组织建模的预测能力.
- 解决传统粘弹性模型的局限性.
主要方法:
- 提出了一种使用反向传播 (BP) 神经网络的新型生物机械建模方法.
- 使用增强的子搜索算法 (ISSA) 来优化BP神经网络模型.
- 混合ISSA-BP模型利用子动态来准确预测放松力.
主要成果:
- 在ISSA优化中集成了混乱映射,非线性惯性权重和交叉策略.
- 该模型表现出极高的精度,猪的R2值为0.9956,猪胃的R2值为0.9896.
- 改进后的模型有效地克服了局部最佳问题,提高了预测性能.
结论:
- ISSA-BP神经网络模型提供了非常准确的软组织放松力预测.
- 这种方法为虚拟手术应用中的生物机械建模提供了一个新且有效的策略.
- 开发的模型增强了虚拟手术培训系统的现实性和有效性.
相关概念视频
Classification of Skeletal Muscle Relaxants
Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
Relaxation of Skeletal Muscles
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open.


