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Updated: May 21, 2025

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增强的α2-3结合化决定了CHO-rVWF的延长半衰期

Ciara Byrne1, Soracha Ward1, Jamie M O'Sullivan2

  • 1Royal College of Surgeons in Ireland, Dublin, Ireland.

Blood
|March 18, 2025
PubMed
概括

再组合的人类·维勒布兰德因子 (CHO-rVWF) 的半衰期比血源VWF (pdVWF) 的半衰期更长. 在CHO-rVWF上增强的α2-3化,而不是α2-6,解释了其延长的循环时间.

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