通过使用等价二极管层模型的各种心室恢复模式,T波的起源
Manon Kloosterman1, Iris van der Schaaf1, Machteld J Boonstra2
1Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
Computers in biology and medicine
|March 18, 2025
概括
一个新的算法,BackRep,可靠地估计心脏恢复时间独立于激活时间. 这种方法支持顶点到底部的恢复模式,影响正常的T波形态.
科学领域:
- 心血管生理学心血管生理学
- 生物医学工程 生物医学工程
- 计算电生理学 计算电生理学
背景情况:
- 相当双极层 (EDL) 模型将心脏电位与身体表面电位联系起来,有助于了解心脏激活和恢复.
- 由于非线性关系,对局部激活时间 (LAT) 和恢复时间 (LRT) 的准确初步估计对于逆心电图中的EDL源模型至关重要.
研究的目的:
- 在等效双极层 (EDL) 源模型中开发一个独立于激活时间的初始恢复时间 (RT) 估计.
- 验证一种用于估计心脏恢复模式及其与T波形态学的关系的新算法.
主要方法:
- 用EDL源模型对15名受试者进行了身体表面映射 (BSM) 和心脏成像,以估计LAT和LRT.
- 开发了一个新的算法BackRep,用于向后T波建模,以识别最新的恢复区域.
- 评估了各种心室恢复模式,包括依赖LAT和基于解剖学的RT差异,以与正常的T波相关联.
主要成果:
- 与基于解剖轴 (CC = 0.29-0.79, RD = 0.61-1.18) 和基于LAT (CC = 0.63, RD = 4.35) 的恢复模式相比,BackRep算法显示出更高的性能 (CC = 0.89,RD = 0.63).
- 基恢复模式显示了在解剖轴之间记录和计算的T波之间最好的相关性.
- 在BackRep的恢复地图中,发现了重要的顶点到底点RT差异.
结论:
- BackRep提供可靠的初始RT估计,独立于激活时间.
- 这些发现支持存在顶点到底点的RT差异,有助于正常的T波形态.
更多相关视频
12:09Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
Published on: January 8, 2013
13.6K
06:57Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
Published on: January 31, 2019
14.4K
相关概念视频
01:30Cardiac Action Potential
728
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
728
01:25Correlation between ECG and Cardiac Cycle
3.0K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
3.0K
01:19Electrophysiology of Normal Cardiac Rhythm
1.9K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
1.9K
01:28Electrocardiogram Fundamentals
471
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
471
01:24Bode Plots Construction
653
The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω):
653
01:29Electrocardiogram
1.9K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
1.9K