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Updated: May 10, 2026

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
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离子通道反应网络:介电选和路外流量的重要性

Hannah Weckel-Dahman1, Ryan Carlsen1, Alexander Daum1

  • 1Department of Chemistry, University of Utah, Salt Lake City, Utah 84112, United States.

Journal of chemical theory and computation
|March 18, 2025
PubMed
概括

多尺度响应动力学建模显示,离子通道机制取决于多个路径和相互作用. 优化这些相互作用提高了效率,并揭示了选如何影响离子流和电流配置文件.

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