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Updated: May 21, 2025

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

Published on: March 23, 2011

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亚慢性服用AM6545可提高认知表现,并诱导海马突触可塑性变化在原始小鼠中

Araceli Bergadà-Martínez1, Lucía de Los Reyes-Ramírez1,2, Sara Martínez-Torres1

  • 1Laboratory of Neuropharmacology-NeuroPhar, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

British journal of pharmacology
|March 19, 2025
PubMed
概括

重复的外围CB1受体对手AM6545在小鼠中改善了记忆力和执行功能. 这表明外围CB1受体是提高认知功能的诺特罗普化合物的新目标.

关键词:
这是一个CB1受体.认知增强 认知增强 认知增强河马突触可塑性 河马突触可塑性从外围到中心的中心.

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Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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