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Updated: May 21, 2025

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无形固体分散/efavirenz盐:研究分子相互作用对再结晶和体内溶解性能的作用

Aastha Gadoya1, Kiran Dudhat2, Sunny Shah1

  • 1B.K. Mody Government Pharmacy College, Polytechnic Campus, Near Ajidam, Rajkot, Gujarat, 360005, India.

AAPS PharmSciTech
|March 19, 2025
PubMed
概括

用Eudragit® E100制备的Efavirenz无形系统表现出增强的稳定性和溶解性. 埃法维伦兹和Eudragit® E100之间的离子相互作用改善了药物负载和超和,克服了生物可用性问题.

关键词:
在体外一步溶解溶解过程中.加速稳定性研究.无形固体的分散性固体.药物聚合物相互作用 药物聚合物相互作用埃法维伦兹 (Efavirenz) 是一种聚合物的无形盐.

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