饮食中的酸负荷与胰岛素抵抗指数之间的关联
Niloufar Abdollahpour1, Najmeh Seifi2, Alireza Abbas Abad Arabi3
1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Scientific reports
|March 19, 2025
概括
饮食中的酸负荷与胰岛素抵抗 (IR) 和心脏代谢问题有关. 较高的酸载荷与较差的IR指数相关,特别是三糖糖-腰围 (TyG-WC) 测量.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 饮食引起的酸不平衡越来越多地被认为是其在胰岛素抵抗 (IR) 和心脏代谢异常中的作用.
- 了解导致IR的特定饮食因素对于预防性健康策略至关重要.
研究的目的:
- 在一大批伊朗成年人中调查饮食中的酸负荷与各种胰岛素抵抗指数之间的关联.
- 为了确定哪些特定的IR指数与饮食中的酸性负载最为密切相关.
主要方法:
- 一项涉及6531名伊朗成年人的横截面研究.
- 饮食中的酸性负荷是使用经过验证的65项食物频率问卷估计的.
- 用多个指数评估胰岛素耐药性:TG:HDL,METS-IR,TyG-BMI,TyG和TyG-WC.
主要成果:
- 所有评估的IR指数在饮食酸负载最高的三分位数的参与者中明显高于最低的参与者 (p < 0.001).
- 最初,在饮食中的酸负荷和TG:HDL,TyG,TyG-WC,TyG-BMI和METS-IR之间观察到显著的积极关联.
- 在完全调整后,甘油三糖 (TyG) 和甘油三糖腰围 (TyG-WC) 仍然与饮食中的酸负载有显著的关联 (分别为OR=1.16和OR=1.69).
结论:
- 饮食中的酸负载与伊朗成年人胰岛素抵抗的多个指数有显著的关联.
- 三甘油糖 - 腰围 (TyG-WC) 显示出与饮食中的酸负载的最强相关性,突出其作为关键指标的潜力.
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