POT是一种基于光遗传学的内源蛋白质降解系统

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Updated: May 21, 2025

Tuning Degradation to Achieve Specific and Efficient Protein Depletion
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Tuning Degradation to Achieve Specific and Efficient Protein Depletion

Published on: July 20, 2019

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Yunyue Chen1, Siyifei Wang1, Luhao Zhang1,2

  • 1Department of Biomedical Engineering, MOE Key Laboratory of Biomedical Engineering, State Key Laboratory of Extreme Photonics and Instrumentation, Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Zhejiang University, Hangzhou, Zhejiang, China.

Communications biology
|March 19, 2025
PubMed
概括

研究人员开发了介导的OptoTrim-Away (POT),这是一种使用来快速降解特定内源蛋白质的新型光遗传系统. 这项技术为细胞生物学和潜在疗法控制蛋白质水平提供了一种新方法.

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