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Updated: May 21, 2025

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一个聚焦于色素的CRISPR屏幕识别了USP22作为阻碍体细胞重编程的障碍

Gülben Gürhan1, Kenan Sevinç1, Can Aztekin1

  • 1School of Medicine, Koç University, Istanbul, Turkey.

Communications biology
|March 19, 2025
PubMed
概括

研究人员发现,抑制Ubiquitin特异性酶22 (USP22) 显著提高了将体细胞重新编程成诱导多能干细胞 (iPSCs) 的效率. 这一发现为改善iPSC生成提供了一个新的目标.

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