相关实验视频

Updated: May 21, 2025

Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
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Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation

Published on: November 10, 2017

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通过PABPC1相分离进行选择性转化控制,调节慢性髓性白血病的爆发性危机和治疗阻力

Chenguang Sun1,2, Xi Xu3,4, Zhongyang Chen1

  • 1State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Key Laboratory of RNA and Hematopoietic Regulation, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.

Nature cell biology
|March 19, 2025
PubMed
概括

聚A结合蛋白细胞质蛋白1 (PABPC1) 驱动慢性髓性白血病 (CML) 爆发危机的进展. 抑制PABPC1可以克服氨酸激酶抑制剂的耐药性,并抑制CML的进展.

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