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败血性关节炎患者的生存率和风险因素分析:对192例病例进行了回顾性研究
Melanie Schindler1,2, Lorenz Huber3, Nike Walter3,4
1Division of Orthopaedics and Traumatology, University Hospital Krems, Karl Landsteiner University of Health Sciences, Dr. Karl-Dorrek-Straße 30, Krems, 3500, Austria.
BMC infectious diseases
|March 19, 2025
概括
败血性关节炎 (SA) 的死亡率很高,特别是在患有慢性病或恶性瘤等并发症的老年患者中. 早期干预和监测对于改善这些脆弱个体的结果至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
- 临床医学 临床医学
背景情况:
- 败血性关节炎 (SA) 带来了严重的发病率和死亡率挑战.
- 了解SA中的死亡预测因素对于患者管理至关重要.
研究的目的:
- 评估败血性关节炎患者的整体死亡率.
- 为了确定与SA增加的死亡率相关的风险因素.
主要方法:
- 在德国一所大学医院 (2011-2021) 对192名SA患者的回顾性分析.
- 使用ICD-10代码进行患者识别和数据提取.
- 卡普兰-梅尔生存分析和几率比率 (OR) 用于确定死亡风险因素.
主要成果:
- 一个由192名患者组成的队列显示,平均随访时间为54.4个月,死亡率为33.3%.
- 在65岁以上的患者和患有高血压,心力衰竭,慢性病,肝病,恶性瘤,类固醇使用和免疫抑制的患者中观察到显著的死亡风险.
- 慢性病 (OR=2.80),恶性瘤 (OR=3.40) 和慢性心力衰竭 (OR=2.62) 被确定为主要死亡率预测因素.
结论:
- 败血性关节炎与高死亡率有关,特别是在患有先前并发症的患者中.
- 早期识别和管理风险因素,如慢性器官疾病和败血症,对于降低SA死亡率至关重要.
- 密切的患者监测和及时干预可以改善脆弱的SA人群的结果.
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