NPM1突变亚型和共突变模式对急性髓性白血病结果的影响

Kittika Poonsombudlert1, Ratdanai Yodsuwan1, Sarah Mott1

  • 1University of Iowa Health Care, Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.

PubMed
概括

在各个亚型中,NPM1突变AML的预后并没有显著差异. 然而,像KRAS,TET2,IDH1/IDH2和SRSF2这样的共同突变以及白细胞计数会影响结果,这表明这些是关键的预后因素.

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