比较人工智能模型在预测卵巢癌存活率方面的有效性:一个系统性审查
Farkhondeh Asadi1, Milad Rahimi1, Nahid Ramezanghorbani2
1Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Cancer reports (Hoboken, N.J.)
|March 19, 2025
概括
机器学习 (ML) 模型对预测卵巢癌 (OC) 存活率充满希望,但准确性和解释性仍然存在挑战. 整合不同类型的数据是提高预测精度的关键.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 数据科学数据科学数据科学
背景情况:
- 卵巢癌 (OC) 生存预测对于患者管理至关重要.
- 机器学习 (ML) 为预后建模提供了先进的分析能力.
- 系统性审查,以评估OC生存预测中的ML算法的有效性.
研究的目的:
- 评估ML算法来预测卵巢癌的整体存活率 (OS),无复发存活率 (RFS),无进展存活率 (PFS) 和治疗反应.
- 确定影响OC ML模型预测准确性的关键特征.
- 评估ML在卵巢癌预后中的当前情况和未来方向.
主要方法:
- 在PubMed,Scopus,Web of Science和Cochrane数据库中的系统文献搜索.
- 包括过去十年内发表的32项研究,重点关注2021年后的最新进展.
- 分析常用的ML算法 (如随机森林,SVM,深度学习) 和评估指标 (AUC,C指数,准确性).
主要成果:
- 常见的ML算法包括随机森林,支持向量机,后勤回归,XGBoost和深度学习.
- 曲线下的面积 (AUC),一致性指数 (C指数) 和准确性是经常使用的评估指标.
- 确定的显著预测因素包括诊断时的年龄,瘤阶段,CA-125水平和治疗因素.
结论:
- ML模型显示了预测卵巢癌生存结果的巨大潜力.
- 需要解决模型准确性和可解释性的挑战.
- 整合多种数据类型 (临床,成像,分子) 与多式机器学习方法的整合对于提高预后精度至关重要.
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