在类风湿性关节炎研究 (LUTH-RA) 中的下泌尿道症状和血
1Abrar Ahmed Wagan, MBBS, FCPS (Medicine), FCPS (Rheumatology), FACR Associate Professor of Rheumatology, Indus Medical College, Tando Mohammad Khan, Sindh, Pakistan.
Pakistan journal of medical sciences
|March 19, 2025
概括
低尿路问题和微观出血在类风湿性关节炎患者中很常见. 疾病严重程度的增加与更多的尿路症状和生活质量的降低有关.
科学领域:
- 类风湿病学 类风湿病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 临床研究 临床研究
背景情况:
- 类风湿性关节炎 (RA) 是一种慢性自身免疫性疾病.
- RA 可以影响各种器官系统,包括泌尿道.
- 了解RA中尿路问题的患病率对于全面的患者护理至关重要.
研究的目的:
- 为了确定类风湿性关节炎队列中血液和下泌尿道问题的频率.
- 调查类风湿性关节炎疾病活动与尿路症状之间的关联.
主要方法:
- 一项涉及229名RA患者的横截面前性研究.
- 数据收集包括人口统计细节,布里斯托尔女性下尿道问卷 (BFLUTS),男性前列腺超声波和微观尿液分析.
- 使用DAS-28.8.进行疾病活动评估.
主要成果:
- 下尿道症状 (LUTS) 的患病率为77.3%,微观出血率为34.5%.
- 常见的LUTS包括夜尿 (69%),膀疼痛 (35.4%) 和尿失禁 (24.5%).
- 观察到DAS-28得分与LUTS和微观出血症 (p<0.01) 之间存在显著的关联.
结论:
- 在男性和女性RA患者中,下泌尿道问题和微观出血都很普遍.
- 风湿性关节炎的严重程度增加与LUTS的发病率更高以及对生活质量的负面影响有关.
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