肉衍生物对糖尿病有效和安全吗?
Methiye Mancak1, Ufuk Koca Çalişkan1,2
1Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkiye.
Turkish journal of medical sciences
|March 19, 2025
概括
肉通过抑制关键酶来表现出抗糖尿病的特性. 然而,一些商业肉产品含有高胺含量,这可能会对健康造成风险,并且需要仔细采购治疗用途.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 食品科学 食品科学 食品科学
背景情况:
- 肉 (属 *Cinnamomum*) 是从树皮中提取的,因其在传统上用于治疗糖尿病而得到广泛认可.
- *Cinnamomum*属包括大约250个物种,其中*C. verum*,*C. cassia*,*C. burmannii*和*C. loureiroi*在商业上普遍存在.
- 以前的研究强调了肉及其副产品的抗糖尿病潜力.
研究的目的:
- 为了评估各种商业肉样本的化学成分.
- 评估这些肉样本的体外抗糖尿病活性.
- 为了确定商用肉在与健康相关的应用中的安全性.
主要方法:
- 对七个不同的肉样品 (棒,茶袋,囊) 进行了宏观和色谱分析.
- 进行了酶抑制测定,针对与糖尿病相关的酶:α-氨酶,α-葡萄糖酶和阿尔多减少酶.
- 使用高性能液态染色学 (HPLC) 来量化关键化合物,超甲和氨酸.
主要成果:
- 肉提取物显著抑制了与糖尿病相关的酶.
- 跨甲水平在7.73-333.69毫克/克之间,氨酸水平在水和乙醇提取物中达到43.73毫克/克.
- 在 *C. cassia*, *C. burmannii* 和 *C. loureiroi* 提取物中检测到高度的库马林,这可能表明根据欧洲食品安全局的指导方针存在健康风险.
- 尽管观察到抗糖尿病活性,但通过HPLC在已成品草药产品中没有检测到跨甲和氨酸.
结论:
- 肉的植物性来源对于其在和治疗环境中的安全应用至关重要.
- 这项研究强调了严格的质量控制和检查草本来源的肉产品的必要性.
- 化学成分的变化需要仔细选择肉,以获得健康益处和安全保证.
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