膝关节神经阻断与膝关节神经切除膝关节骨关节炎:随机对照试验和回顾性研究的系统审查
Ammar Yaser Mohammad Toubasi1, Amanda Myles2,3, Paramvir Singh4,5
1Anesthesiology and Perioperative Medicine, Augusta University Medical College of Georgia, Augusta, USA.
Cureus
|March 19, 2025
概括
生殖器神经切除和生殖器神经阻断 (GNB) 有效地管理膝关节骨关节炎 (OA) 疼痛并改善功能. 切除可能比诊断阻断提供更持久的缓解,但它对治疗阻断的优势需要进一步研究.
科学领域:
- 疼痛管理 疼痛管理
- 整形外科 整形外科 整形外科
- 干预性疼痛医学 干预性疼痛医学
背景情况:
- 膝关节关节炎 (OA) 是慢性疼痛和残疾的主要原因.
- 目前治疗膝关节OA疼痛的方法存在局限性.
- 阴茎神经干预提供了一种最小的侵入性方法来缓解疼痛.
研究的目的:
- 系统地审查和比较生殖神经切除与生殖神经阻断 (GNB) 的疗效和安全性,用于膝盖OA.
- 评估接受这些手术的患者的疼痛控制和功能改善.
主要方法:
- 随机对照试验 (RCT) 和回顾性研究的系统审查.
- 搜索了主要的数据库 (PubMed,谷歌学者等). 在2023年4月之前.
- 主要结局:视觉模拟尺度 (VAS) 和数值评分尺度 (NRS) 对疼痛;次要结局:WOMAC评分和并发症.
主要成果:
- 膝关节神经切除和GNB都在膝关节OA患者中显示出显著的疼痛减轻和功能改善.
- 与诊断阻塞相比,阴茎神经切除可能会提供更实质和更长时间的疼痛缓解.
- 切除和使用类固醇的治疗阻断之间,功能能力的改善是可比的.
- 对于这两种干预措施,不良事件是最小的和短暂的.
结论:
- 膝关节神经切除和GNB是治疗膝关节OA疼痛和改善功能的有效策略.
- 阴茎神经切除显示出优越和持续的疼痛缓解的潜力,需要进一步调查.
- 这两种程序都表现出良好的安全概况,并具有最小的不良事件.
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