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综合饮食抗氧化剂指数与全因死亡率之间的性别差异

Lanzhi Duan¹, Rui Zeng², Jiang Wang¹

¹Department of Public Health, School of Basic Medical Sciences, Jinggangshan University, Ji'an, Jiangxi, China.

Frontiers in nutrition

|March 19, 2025

概括

综合饮食抗氧化剂指数 (CDAI) 与较低的全因死亡风险有关,但这种关联仅在男性中具有意义. 性别在饮食和死亡风险之间的关系中起着关键作用.

科学领域:

营养科学营养科学
流行病学流行病学
公共卫生公共卫生

背景情况:

关于综合饮食抗氧化剂指数 (CDAI) 与全因死亡率之间的关联存在争议.
以前的研究对饮食中抗氧化剂对死亡率的影响产生了相互矛盾的结果.
性别对CDAI-死亡率关系的影响仍未得到充分研究.

研究的目的:

在大量成年人群中调查CDAI和全因死亡率之间的关联.
确定性别是否改变了CDAI和全因死亡率之间的关系.
为减少死亡风险的饮食策略提供基于证据的见解.

主要方法:

分析2001年至2018年国家健康和营养检查调查 (NHANES) 成年参与者 (年龄≥18) 的数据.
将NHANES数据与NHANES公共使用链接死亡档案联系起来,以确定所有原因的死亡率.
使用受限立方线和多变量考克斯回归分析来评估性别的关联和子组差异.

主要成果:

这项研究共包括了15651名个人.
在CDAI和全因死亡率之间观察到显著的反向关联,特别是在CDAI值低于5的情况下.
与较高的CDAI相关的全因死亡风险降低主要观察到男性,性别有显著的相互作用效应 (p < 0.001).

结论:

较高的综合饮食抗氧化剂指数 (CDAI) 与所有原因死亡的风险降低有关.
这种保护性关联是特定于成年男性的,突显了性别的重大影响.
饮食中的抗氧化剂摄入量可能会根据性别在死亡风险中起到不同的作用.

关键词:

尼汉斯 (NHANES) 是一个名人.所有原因的死亡率.抗氧化剂指数抗氧化剂指数综合饮食组合饮食组合性别差异的性别差异是什么

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