黄素对绝经后妇女健康的影响:系统性审查和元分析
Dachuan Jin1, Shunqin Jin2, Guoping Sheng3
1Affiliated Infectious Disease Hospital of Zhengzhou University (Henan Provincial Infectious Disease Hospital, Zhengzhou Sixth People's Hospital), Zhengzhou, People's Republic of China.
Phytotherapy research : PTR
|March 19, 2025
概括
黄素补充有益于更年期后妇女,改善心血管健康,减少氧化应激,缓解血管运动症状. 需要进一步的研究来证实这些影响,因为研究的变化.
科学领域:
- 妇女健康 妇女健康
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 更年期与心血管风险增加,氧化应激和代谢变化有关.
- 黄中发现的黄是一种化合物,具有抗氧化和抗炎性质.
- 关于黄素在绝经后妇女的疗效的证据需要进行系统的评估.
研究的目的:
- 进行一项元分析,评估黄素对绝经后妇女各种健康指标的影响.
- 综合关于黄素补充的随机对照试验 (RCT) 的发现.
- 评估黄素对心血管健康,氧化应激,骨健康,代谢健康和生活质量的影响.
主要方法:
- 在PubMed,Embase,Cochrane图书馆和Web of Science的系统文献搜索,截至2024年7月.
- 包括14项随机对照试验,共982名参与者.
- 使用Cochrane风险偏见工具进行质量评估.
主要成果:
- 黄素显著降低了静缩和静缩血压.
- 观察到增加的总抗氧化能力和超氧化物脱酶水平.
- 黄素降低了阿斯巴酸胺转移酶 (AST) 和改善了血管运动症状.
结论:
- 在绝经后的妇女中,黄素对心血管风险因素,氧化应激,肝酶和血管运动症状产生积极影响.
- 这些发现表明黄素在管理更年期健康方面具有潜在的治疗作用.
- 限制包括黄素纯度和剂量的变化,需要更大,更全面的试验和机制研究.
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