胸部计算机断层扫描 发散性血清的发现 在先进的艾滋病毒疾病中
Alessandro C Pasqualotto1,2, Lisandra S Damasceno3,4, Terezinha M J S Leitao3,4
1Federal University of Health Sciences of Porto Alegre (UFCSPA), Porto Alegre, Brazil.
Mycoses
|March 19, 2025
概括
在晚期艾滋病毒疾病中传播性基因质瘤呈现出可变的胸部CT发现,通常是不特定的. 在CT扫描中的微节模是免疫受损患者在特有病区的关键指标.
科学领域:
- 医疗成像医学成像
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 传播性基因质瘤是一种严重的机会性感染,发生在晚期艾滋病毒疾病 (AHD) 患者身上.
- 由于非特定的临床和成像发现以及传统诊断方法的局限性,延迟诊断是常见的.
研究的目的:
- 为了评估胸部计算机断层扫描 (CT) 结果在患有散布性基因质和AHD的患者.
- 为了确定与这种机会性感染相关的放射性模式.
主要方法:
- 在II期临床试验中对38名患者的高分辨率胸部CT扫描进行分析.
- 对肺部异常进行放射性评估,包括结节,地面玻璃衰减和淋巴腺病变.
- 临床表现,共感染和系统性发现的文档.
主要成果:
- 所有患者都表现出异常的胸部CT检测结果,其中军脉结节 (89.5%) 和地面玻璃衰减 (86.8%) 是最常见的.
- 中淋巴腺病 (84.2%) 和大结节 (73.8%) 是常见的;空洞结节发生在26.3%的人中.
- 报告的肺部症状为65.8%,体重减轻为73.7%,并发感染在36.8%的患者中检测到.
结论:
- 胸部CT检测结果在扩散性基因质瘤是可变的和非特异性的,具有挑战性的诊断.
- 胸部CT上的分散的微状图案应该使人们怀疑在特有地区的基因质粒症.
- 早期识别至关重要,特别是在患有晚期艾滋病毒疾病的免疫功能低下个体中.
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