评估在脑膜切除或安置管在头部和部癌症后的不良结果
Krithika Kuppusamy1, Carly Y Yang1, Kevin Wong1
1Department of Otolaryngology-Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.
概括
在脑膜切除术后,有头癌病史的患者面临持续性鼓膜穿孔的风险更高. 这项研究强调了穿孔率的增加,强调了在这个患者群体中需要仔细考虑的必要性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 医学成果研究研究成果
背景情况:
- 中耳溢出是很常见的,通常用带管或不带管管安置的线索切除术来治疗.
- 患有头癌病史的患者可能具有独特的风险因素,在听力学手术后出现不良结果.
研究的目的:
- 评估和比较患有和没有头癌病史的患者中不良结局的发生率,这些患者接受了带有或没有插入中耳输液管的脑膜切除术.
主要方法:
- 在2018年至2022年期间,在一个学术医疗中心对578名患者 (84人有头癌史) 的回顾性图表审查.
- 收集的数据包括人口统计,癌症史,听力测量和临床过程.
- 倾向性得分匹配用于控制混变量.
主要成果:
- 在癌症和非癌症队列中,整体不良结局率相似 (44.05%与44.13%).
- 患有头部和部癌症病史的患者患有持续的耳膜穿孔率显著更高 (14.29%与2.43%,P < .001),在倾向性得分匹配 (14.29%与1.22%,P < .01) 后仍然显著.
- 复发的中耳溢出率在两组之间没有显著差异.
结论:
- 头部和部癌症的病史,特别是与辐射有关,与 myringotomy 后持续的耳膜穿孔的风险显著增加有关.
- 虽然整体不良事件发生率相似,但较高的穿孔风险在这个人群中需要特别注意.
- 穿孔风险似乎是多因素的,需要进一步调查.
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