气道异常预测了儿童肺高血压的风险
Elana R Kriegel1, Aditya Srinivasan1, Luke Mammen2
1Albany Medical College, Albany, New York, USA.
儿科肺高血压 (PH) 与心脏和呼吸道问题有关,特别是在患有支气管肺功能障碍的婴儿中. 多学科团队的早期查对于患有多种并发病的高风险儿童至关重要.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 儿科肺病学 儿科肺病学
- 医学遗传学 医学遗传学
背景情况:
- 儿科肺高血压 (PH) 是一种严重的疾病,导致右心力衰竭和缺氧.
- 儿童的PH和呼吸道异常之间的关联是复杂的,需要进一步了解.
- 识别有风险的儿科患者进行PH查对于及时干预至关重要.
研究的目的:
- 调查儿科肺高血压与同时发生的心肺异常之间的关联.
- 确定与儿童PH风险增加相关的特定先天性疾病.
- 为儿童PH的查指南的制定提供信息.
主要方法:
- 从2021年1月到2023年1月对儿科患者进行的回顾性,观察性,横截面研究.
- 分析住院,急诊室和手术室记录.
- 利用几率比率和逻辑回归来确定PH与其他异常之间的关联.
主要成果:
- PH与心脏和呼吸道异常显著相关 (OR 3.26,p<0.05).
- 关键的相关疾病包括支气管肺功能障碍 (BPD),心房隔膜缺陷 (ASD),心室隔膜缺陷 (VSD),专利导管动脉 (PDA) 和慢性肺病 (CLD).
- 唐氏综合征 (DS) 也被发现与PH有关.
结论:
- 儿科PH经常与其他心肺异常同时发生,这表明患有多种并发症的患者的风险很高.
- 多学科护理团队应对高风险儿科患者进行PH的查.
- 在多个地点进行进一步的研究和量化可以帮助完善PH查指南.
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