贝塔的恶性混合虹膜-黑色素瘤与同时存在的Mycobacterium chelonae隔离-A病例报告
Zi An Yu1, Lorraine A Corriveau2, Joanne B Messick1
1Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, West Lafayette, Indiana, USA.
Journal of fish diseases
|March 19, 2025
概括
在一个罗战斗鱼 (Betta splendens) 的恶性瘤被确定为混合细胞虹膜-黑色素瘤. 同时还检测到Mycobacterium chelonae感染,这表明需要进一步调查的潜在联系.
科学领域:
- 水生动物病理学
- 鱼类瘤学 鱼类瘤学
- 比较病理学比较病理学
背景情况:
- 染色体瘤是影响鱼类色素细胞的瘤.
- 这些瘤的恶性表现不太常见.
- 同时感染可能会使诊断和治疗复杂化.
研究的目的:
- 报告一个恶性染色体瘤病例在一个罗战斗鱼.
- 调查并发的病理发现,包括传染病原体.
- 突出瘤和鱼类感染之间的潜在关联.
主要方法:
- 临床检查和诊断成像.
- 印象细胞学,组织病理学和传输电子显微镜 (TEM) 用于瘤特征.
- 细菌培养和分子鉴定 (rpoB和16S rRNA的桑格测序,BLAST分析) 针对传染病原体.
主要成果:
- 诊断出一种具有恶性特征的混合细胞虹膜 - 黑色素瘤.
- 瘤呈现出快速生长,异型,入侵和栓塞.
- 发现了轻微的单核性炎症.
- 从受影响的鱼中分离并鉴定出Mycobacterium chelonae.
结论:
- 这一病例代表了第一份关于恶性 piscine 染色体和同时感染 Mycobacterium 的报告.
- 这些发现表明,瘤和鱼类中的真菌细菌感染之间存在潜在的关联.
- 需要进一步的研究来探索这种潜在的联系及其对鱼类健康的影响.
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