在2019年冠状病毒疾病中的怀孕和分娩结果:来自高等中心的横截面研究
Suzan Şahin1, Bülent Kaya1, Emre Mat2
1Kartal Dr. Lütfi Kırdar City Hospital, Department of Infectious Diseases and Microbiology - İstanbul, Türkiye.
概括
患有2019年新冠病毒病 (COVID-19) 的孕妇面临着严重的孕产妇和分娩并发症,包括早产和低出生体重. 在这些病例中,甲状腺功能低下是常见的并发症.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 怀孕呈现出独特的生理变化,可以改变对感染的易感性和反应.
- 冠状病毒疾病2019 (COVID-19) 已成为全球健康问题,需要了解它对孕妇等弱势群体的影响.
研究的目的:
- 记录诊断出COVID-19的孕妇的临床和实验室特征.
- 分析COVID-19的孕妇的孕产妇和分娩结果.
主要方法:
- 对2020年3月至2023年1月期间因COVID-19住院或分娩的孕妇的回顾性评估.
- 对两个队列的评估:住院的COVID-19孕妇和在大流行期间分娩的孕妇.
- 对临床数据,实验室结果,并发症和分娩结果的分析.
主要成果:
- 总共有295名孕妇被纳入初始队列,疾病严重程度不同,甲状腺功能低下是最常见的并发症 (13.6%).
- 升高的D-二聚物水平是最常见的实验室异常 (94.6%).
- 在分娩队列中 (193名妇女),4.1%需要接受ICU治疗,2.6%的死亡率,61.2%的剖腹产是紧急情况. 观察到早产 (18.7%),低出生体重 (14.5%) 和死产 (3.1%). 中度至重度的COVID-19与分娩周,出生体重和APGAR分数相反相关.
结论:
- 患有COVID-19的孕妇有很大的孕产妇和分娩并发症的风险,包括早产和低出生体重的婴儿.
- 甲状腺功能低下症被确定为COVID-19的孕妇中显著的并发症.
- 怀孕期间COVID-19的严重程度与新生儿不良结果有关.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
5.0K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.0K
Pneumonia III: Complications and Assessment
1.4K
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.4K
Intrauterine Drug Delivery Systems
169
Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
169
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
760
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
760
Development of the Oral Microbiota
73
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
73
Cytomegalovirus Disease
108
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
108


