素水解剂增强了猪上部胃肠道的化学传感和胃酸分泌
Chunlong Mu1, Junhua Shen1,2, Huisong Wang1,2
1Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Journal of agricultural and food chemistry
|March 19, 2025
概括
饮食中的素解剂增强了猪的胃酸分泌和化学感应. 这种营养策略可以通过调节消化系统来改善氨基酸消化和营养利用.
科学领域:
- 动物营养 动物营养
- 胃肠病学 胃肠病学
- 生理学 生理学 生理学
背景情况:
- 胃化学传感和酸分泌对于营养利用至关重要.
- 类对胃功能的影响尚不清楚.
研究的目的:
- 为了研究胺丰富的素化物对猪胃化学感应和酸分泌的影响.
- 为了比较胃对化素和完整的素的反应.
主要方法:
- 使用16只猪进行了为期28天的养试验,比较了使用完整素和化素的饮食.
- 胃酸 (盐酸) 度,表皮细胞数和H+-K+-ATPase活性的分析.
- 测量化传感器表达 (GPCR92,CaSR) 和胃组织和舌头中的信号通路组件.
- 在胃消化器中评估素活性和氨基酸度.
主要成果:
- 素水解剂显著增加了胃盐酸,表皮细胞和H+-K+-ATPase活性.
- 胃和舌头中的胃化学传感通路 (GPCR92,CaSR) 的升级.
- 增强胃酸分泌的信号通路,包括刺激和受体.
- 增加素活性和降低胃消化器中的氨基酸度.
结论:
- 饮食中的素解剂有效地增强了猪的胃化学传感和酸分泌.
- 这表明了优化氨基酸消化和营养吸收的潜在营养策略.
- 这些发现提供了关于食酸对消化过程的生理调节的见解.
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