结直肠癌患者的核心症状,功能和生活质量之间的关系:网络分析
Wenqian Qi1, Ruzhen Zhou2, Qun Qiu2
1Department of Nursing, Naval Medical University, 800 Xiangyin Rd, Yangpu District, Shanghai, China.
概括
疲劳和疼痛等核心症状对结直肠癌患者在手术后的影响. 管理策略必须根据口腔静脉的存在来个性化,以改善生活质量.
科学领域:
- 在瘤学瘤学.
- 症状科学 症状科学
- 生活质量研究 研究 生命质量研究
背景情况:
- 大肠直肠癌 (CRC) 显著影响患者的功能状态和生活质量 (QoL).
- 了解核心症状及其与QoL的关系对于有效的患者管理至关重要.
- 手术后的管理往往需要量身定制的方法,特别是关于静脉的存在.
研究的目的:
- 为了确定接受结直肠癌手术的患者所经历的核心症状.
- 调查这些核心症状,功能状态和整体生活质量之间的相关性.
- 根据静脉口腔的存在或不存在来区分症状概况和QoL关联.
主要方法:
- 分析了511名接受了结直肠癌手术 (带或不带口腔) 的成年患者队列.
- 使用了欧洲癌症研究和治疗组织的生命质量问卷核心30 (EORTC-QLQ C30) 和结肠直肠癌模块 (EORTC-QLQ CR29).
- 在R的网络分析中,根据中心性确定了核心症状,并使用引导网包评估了稳定性.
主要成果:
- 疲劳和疼痛被确定为常见的核心症状,既在静脉管和非静脉管组.
- 胃口丧失是没有口腔静脉瘤的患者特有的,而对口腔静脉瘤患者来说,身体形象问题是核心问题.
- 焦虑,尽管它的流行,并没有被确定为核心症状;情绪功能介导的 QoL 在非口腔患者,不像口腔患者.
结论:
- 对于有或没有胃口的结肠直肠癌患者来说,需要明确的临床途径来增强QOL.
- 在早期的术后期,个性化症状管理策略至关重要.
- 解决诸如身体形象之类的静脉管特定问题对于改善患者的治疗结果至关重要.
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