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儿童肥胖体重指数和肠道微生物组:一个集群随机控制试点可行性研究
Marilyn Frenn1, Nita Salzman2,3, Vy Lam2
1Marquette University College of Nursing, Milwaukee, Wisconsin, USA.
Childhood obesity (Print)
|March 19, 2025
概括
益生菌纤维的摄入可能有助于通过改变肠道细菌来降低风险年轻人的体脂和BMI. 进一步的研究可以个性化推饮食纤维含量.
科学领域:
- 营养科学 营养科学
- 微生物组研究 微生物组研究
- 儿科健康 儿科健康
背景情况:
- 益生菌纤维正在探索减肥,但研究往往不包括有风险的年轻人群.
- 肥胖不成比例地影响着非洲裔美国人和拉丁裔青年,突出了针对性干预的需要.
- 对益生菌纤维的个体反应取决于现有的肠道微生物群,受到饮食和体育活动的影响.
研究的目的:
- 评估益生菌纤维补充剂的可行性和影响,结合风险青少年饮食和体育活动的数字健康计划.
- 在儿科群体中调查益生菌纤维摄入量,身体组成的变化和肠道微生物群的变化之间的关系.
主要方法:
- 一项为期12周的集群随机控制可行性试验,涉及来自低收入背景的123名4年级和5年级学生.
- 干预包括在线计划,以改善饮食和体育活动,并与益生菌纤维管理一起.
- 干预前后评估身体脂肪,BMI和便微生物群组成.
主要成果:
- 身体脂肪的减少与更高的基线身体脂肪有关.
- 下肢体质量指数 (BMI) 与便*Tenericutes*的减少和*Actinobacteria*的增加相关.
- 该干预措施在这个处于风险的青年群体中证明了可行性.
结论:
- 益生菌纤维显示出调节肠道微生物群的潜力,并影响年轻人的身体组成.
- 了解个人对益生菌纤维的反应,可以为预防肥胖提供个性化的饮食建议.
- 这项研究为更大规模的试验提供了基础,这些试验将在多种不同儿科群体中检查益生菌纤维干预措施.
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