成年期吸烟与丹麦男性与年龄相关的认知衰退之间的联系
Erik Lykke Mortensen1,2, Kristine Hell1,3, Gunhild Tidemann Okholm1,4
1Unit of Medical Psychology, Section of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
PloS one
|March 19, 2025
概括
这项研究发现,吸烟与与年龄相关的认知能力下降有微弱的关联,目前的吸烟者比前吸烟者略有下降. 包装年表明轻微的累积效应,但吸烟不是认知能力下降的强有力的预测因素.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 公共卫生 公共卫生
背景情况:
- 以前关于吸烟和认知衰退的研究经常比较组 (吸烟者与非吸烟者),而不是量化累积暴露.
- 调查吸烟包装年的影响提供了对认知衰老的长期影响的更细致的理解.
研究的目的:
- 分析吸烟与与年龄相关的认知衰退之间的联系,用包年来衡量.
- 使用纵向设计,比较当前吸烟者,前吸烟者和从未吸烟者的认知衰退.
主要方法:
- 利用了来自5052名年轻成年和中年后期智力测试成绩的男性的数据.
- 根据自19岁起自述的吸烟史,计算了包装年.
- 采用线性回归模型来分析与吸烟状况和包装年有关的认知衰退.
主要成果:
- 吸烟变量只显示出与认知衰退的弱相关性.
- 成年吸烟者表现出比非吸烟者更少的认知衰退 (1.12智商点).
- 当前吸烟与比以前吸烟 (1.73智商点) 更大的认知衰退有关,独立于包装年.
结论:
- 吸烟不是与年龄相关的认知衰退的强有力的预测因素,解释了可以忽略不计的差异.
- 包装年数表明,在成年人一生中,吸烟的累积效应很弱.
- 观察到的差异可能受到参与偏差,选择性消耗或与当前吸烟相关的生活方式因素的影响.
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