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Updated: May 21, 2025

Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice
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MG53通过无处不在的ATF2进行保护,防止败血性心脏功能障碍

Miao Tian1, Yu Shi1, Xue Gong1

  • 1Department of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing, PR China; Key Laboratory of Geriatric Cardiovascular and Cerebrovascular Disease Research, Ministry of Education of China, Chongqing, PR China; Chongqing Key Laboratory for Hypertension Research, Chongqing Cardiovascular Clinical Research Center, Chongqing Institute of Cardiology, Chongqing, PR China.

Journal of advanced research
|March 19, 2025
PubMed
概括

三重-53 (MG53) 通过减少炎症和改善存活率,在败血症期间保护心脏功能. MG53通过ATF2无化抑制TLR4表达来实现这一目标,为败血性心脏功能障碍提供了潜在的治疗方法.

关键词:
在ATF2中使用ATF2.细胞灭亡 (apoptosis) 是一种死亡的过程.炎症 炎症是一种炎症.MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53MG53M败血性心脏功能障碍是什么在 TLR4 中,

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