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Updated: May 21, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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通过肝脏有机离子运输多类的他类药物的比较吸收

Wilma Kiander1, Alli Sinokki2, Mikko Neuvonen3

  • 1Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, FI-00014 Helsinki, Finland; Department of Clinical Pharmacology, Faculty of Medicine, University of Helsinki, FI-00014 Helsinki, Finland; Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki, FI-00014 Helsinki, Finland; Department of Clinical Pharmacology, HUS Diagnostic Center, Helsinki University Hospital, FI-00029 Helsinki, Finland.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|March 19, 2025
PubMed
概括

这项研究以有机离子运输多 (OATPs) 1B1,1B3和2B1.1为特征. OATP1B1携带所有他类药物,其中疏水性他类药物表现出比水友性他类药物更高的亲和力,有助于理解药物相互作用.

关键词:
这是一个OATP1B1B1的OATP.这是一个OATP1B3B3的OATP.这是一个OATP2B1B1的OATP2B1B1.药理动力学 药理动力学西姆瓦斯塔丁酸是什么史塔丁类药物是一种运输商 运输商 运输商

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