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美国炎症性肠道疾病的老年人流行病学:2000-2021年
Pojsakorn Danpanichkul1, Yanfang Pang2,3,4, Chawinthorn Vuthithammee5
1Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA. pojsakorndan@gmail.com.
Digestive diseases and sciences
|March 20, 2025
概括
在老年人中,炎症性肠病 (IBD) 的发病率正在上升,特别是在女性中,观察到残疾率增加. 这一趋势需要有针对性的策略来管理这个人口群体中IBD负担的增加.
科学领域:
- 老年医学 老年医学
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 美国老龄化人口正在经历炎症性肠病 (IBD) 的发病率和流行率不断增加.
- 老年人 (70岁以上) 在IBD患者中占有显著且不断增长的比例.
- 了解老年人中IBD的趋势对于公共卫生规划至关重要.
研究的目的:
- 为美国70岁及以上的成年人提供IBD负担的最新估计.
- 从2000年到2021年分析IBD发病率,流行率和残疾调整寿命年 (DALYs) 的变化.
- 检查老年人中IBD趋势的性别和州级变化.
主要方法:
- 全球疾病负担分析研究2021年美国70岁以上成年人的数据.
- 按性别和状态对IBD发病率,流行率和DALY进行分层划分.
- 应用Joinpoint回归来评估2000年至2021年年龄标准化利率变化.
主要成果:
- 在2021年,在70岁以上的美国成年人中,有11,250例IBD新病例,180,880例流行病例和80,410例DALY.
- 老年成人发病IBD占IBD总人口的15%,自2000年以来增加了3%.
- 发病率 (APC:0.58%) 和DALY率 (APC:0.34%) 增加,但患病率保持稳定;女性的发病率不成比例地增加.
结论:
- 从2000年到2021年,老年人发病IBD的发病率和残疾率在美国均有所增加.
- 虽然男性最初的发病率较高,但老年女性的发病率增加得更为显著.
- 越来越多的老年人患有IBD和相关残疾的比例强调了需要有针对性的干预措施.
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