中心敏感化对TKA外科手术期疼痛的影响:一项回顾性队列研究
Tatsuru Sonobe1, Takuya Nikaido2, Miho Sekiguchi1
1Department of Orthopedic Surgery, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima-Shi, Fukushima, 960-1295, Japan.
Knee surgery & related research
|March 20, 2025
概括
中枢敏感性 (CS) 对严重膝关节关节炎 (KOA) 的全膝关节关节整形术 (TKA) 之前和之后的膝关节疼痛产生负面影响. 然而,TKA有效地缓解疼痛,无论手术前的CS水平如何.
科学领域:
- 整形外科手术 整形外科手术
- 疼痛管理 疼痛管理
- 类风湿病学 类风湿病学
背景情况:
- 严重的膝关节关节炎 (KOA) 通常用全膝关节整形术 (TKA) 治疗.
- 手术前的中央敏感化 (CS) 可能与TKA后的疼痛结果较差有关,但证据有限.
- 这项研究调查了CS对严重KOA的TKA中术后膝盖疼痛的影响.
研究的目的:
- 为了确定中心敏感化 (CS) 对经过全膝关节整形手术 (TKA) 治疗严重膝关节关节炎 (KOA) 的患者外科手术前膝关节疼痛的影响.
主要方法:
- 对66名因严重KOA而接受双边TKA的患者进行了回顾性队列研究.
- 多重线性回归模型分析了CS对膝关节损伤和骨关节炎结局得分 (KOOS) 疼痛子表的影响.
- 评估包括手术前和手术后3个月的KOOS疼痛,CS和疼痛自我有效性.
主要成果:
- CS对手术前和手术后的KOOS疼痛产生了负面影响 (p < 0.05).
- 高疼痛自我有效性积极影响了手术前KOOS疼痛 (p < 0.05).
- CS没有显著影响TKA后KOOS疼痛的改善.
结论:
- 中心敏感性对严重KOA患者TKA前后的膝盖疼痛产生负面影响.
- 膝关节整形术可为严重的KOA提供显著的疼痛缓解,无论手术前的CS.
- 需要进行进一步的研究,以优化CS的KOA患者的疼痛管理.
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