大麻产品改的流行和模式:对WEDINOS数据的分析
Simon Erridge1,2, Martin Hall2, Mikael H Sodergren1,2
1Department of Surgery and Cancer, Imperial College London, London, UK.
Journal of psychoactive drugs
|March 20, 2025
概括
英国的非法大麻通常缺乏大麻素,并含有危险的合成造剂. 这突显了不受管制产品带来的重大健康风险,需要提高消费者意识和政策改革.
科学领域:
- 法医毒理学 法医毒理学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 全球大麻消费量正在上升,特别是在不受监管的市场.
- 这增加了大麻产品中污染物和改剂的暴露风险.
- 非法大麻由于未知的物质而造成潜在的健康危害.
研究的目的:
- 调查英国非法大麻产品中活性化合物和染剂的存在和类型.
- 评估从未受监管来源获得的大麻的安全概况.
主要方法:
- 对向威尔士新兴药物和新物质识别计划 (WEDINOS) 提交的1,635个大麻样本的分析.
- 化学分析以确定天然存在的大麻素和合成 adulterants.
主要成果:
- 42.51%的样本缺乏天然大麻素.
- 9.91%不含任何活性化合物.
- 38.17%的样本包括一种精神活性 adulterant,最常见的是合成大麻素受体激活剂 (26.61%).
结论:
- 不受监管的大麻产品经常含有危险的 adulterants,造成严重的健康风险.
- 迫切需要提高消费者意识和减少危害的战略.
- 迫切需要政策改革和监管执法,以应对非法大麻市场的风险.
相关概念视频
Pharmacovigilance
2.0K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
2.0K
Analysis of Population Pharmacokinetic Data
996
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
996


