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Updated: May 21, 2025

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
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探索益胰岛素蛋白质稳定:对β细胞健康和糖尿病的洞察

Parisima Ghaffarian Zavarzadeh1, Kathigna Panchal1, Dylan Bishop1

  • 1Department of Biological Sciences, East Tennessee State University, Johnson City, TN, United States.

Frontiers in molecular biosciences
|March 20, 2025
PubMed
概括

由胰岛素基因突变和ER压力驱动的胰腺β细胞中的益胰岛素错误折叠导致糖尿病. 了解这些机制为蛋白质错折疾病提供了新的治疗点.

关键词:
贝塔细胞 贝塔细胞 贝塔细胞糖尿病 糖尿病患者 糖尿病患者胰岛素的生物合成.亲胰岛素折叠式蛋白质稳定症是一种蛋白质稳定症.走私和贩运的人口贩运

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