评估在压力支通风过程中启发力度的非侵入性指标之间的一致性
Wen-Yi Lv1,2, Shuai Liu1, Linlin Zhang1
1Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
压力支通风 (PSV) 的非侵入性指标显示出不同的相关性和一致性. 虽然一些指标如 ΔPocc 和 P0.1 显示出中等一致性,但其他指标如 PMI 和 P0.1 缺乏显著的相关性,影响了临床使用.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统生理学 呼吸系统生理学
- 机械通风机械通风机械通风机
背景情况:
- 在压力支通风 (PSV) 过程中精确评估吸气力非常重要.
- 评估启发性努力的非侵入性指标已得到验证,但它们的指标间的相关性和一致性尚未得到充分理解.
- 了解这些关系对于可靠的患者监测至关重要.
研究的目的:
- 调查PSV期间非侵入性启发性努力指标之间的相关性和一致性.
- 为了比较神经临界患者与非神经临界患者的启发性努力的特征.
- 为了澄清不同的非侵入性措施的临床效用.
主要方法:
- 这是一项前性观察性研究,涉及97名患者.
- 收集了三个非侵入性指标:压力肌肉指数 (PMI),呼吸道阻塞期间气道压力的最大负摆动 (ΔPocc),以及在前100毫秒内气道阻塞压力 (P0.1).
- 使用Spearman的等级测试和使用线性加权卡帕分析的协议分析了相关性,比较神经临界和非神经临界组.
主要成果:
- 在PMI和ΔPocc (rho = -0.524) 之间以及在ΔPocc和P0.1 (rho = 0.588) 之间发现了适度的相关性.
- 在PMI和P0.1之间没有观察到显著的相关性 (rho = -0.140).
- 在 ΔPocc 和 P0.1 之间存在适度的协议 (k = 0.459),在 PMI 和 ΔPocc 之间存在公平的协议 (k = 0.362),在 PMI 和 P0.1 (k = 0.134) 之间没有协议.
结论:
- 非侵入性启发性努力指标在PSV期间表现出可变的相关性和一致性.
- ΔPocc和P0.1显示中度的相关性和一致性,而PMI和P0.1缺乏这两者.
- 研究结果表明,在交替使用PMI和P0.1时应谨慎,神经临界患者的潜在差异需要进一步调查.
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