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Updated: May 21, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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以同位素尿素催化对酸盐功能化β-乳酸盐的酶选择性合成

Ffion M Platt1, Yihong Wang1, David B Cordes1

  • 1EaStCHEM, School of Chemistry, University of St Andrews St Andrews Fife KY16 9ST UK ads10@st-andrews.ac.uk.

Chemical science
|March 20, 2025
PubMed
概括

这项研究引入了一种新的方法,用于使用enantioselective循环添加制造含有酸盐的β-lactones. 开发的异尿素催化反应为这些有价值的化合物提供了可扩展和实用的途径.

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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine09:14

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